Paracetamol and Cetirizine Among 156 Combination Drugs Banned by Indian Government

As a significant move to safeguard public health, the Indian government has recently issued an order of implementing 156 Combination Drugs Banned for usage, including well-known medications such as Paracetamol and Cetirizine like combinations. This decision has stirred considerable discussion in both medical and pharmaceutical circles, prompting questions about the implications for patients, healthcare providers, and the industry at large. This article delves into the reasons behind the ban, the specifics of the affected drugs, and the broader context of this regulatory action.

Understanding the Ban

The Indian government’s decision of these 156 Combination Drugs Banned, stems from growing concerns about their safety and efficacy. Combination drugs, which mix multiple active ingredients into a single formulation, have been scrutinized for potentially causing adverse effects and offering limited therapeutic benefits. The central objective of this regulatory measure is to enhance patient safety and ensure that medications used in India meet high standards of quality and effectiveness.

The ban list includes “Aceclofenac 50mg + Paracetamol 125mg tablet.” which is one of the popular combinations of pain-relieving medicines manufactured by Indias top pharma companies.

The banned list also includes Mefenamic Acid Paracetamol Injection, Cetirizine HCl Paracetamol Phenylephrine HCl, Levocetirizine Phenylephrine HCl Paracetamol, Paracetamol Chlorpheniramine Maleate Phenyl Propanolamine and Camylofin Dihydrochloride 25 mg Paracetamol 300mg which is also a popular dosage used in various pain relief treatments.

What Are Combination Drugs?

Combination drugs are pharmaceutical formulations that contain two or more active ingredients combined into a single dosage form. They are commonly used to treat various conditions by targeting multiple pathways or symptoms simultaneously. For example, a combination drug might include an analgesic (pain reliever) and an antihistamine (allergy relief) to address both pain and allergic reactions in one pill.

As per the notification issued in earlier year dated 10-March-2016 govt. issued a list of banned manufacturing & usage of below 344 dugs & its combinations to stop the possible mass health issues which includes these 156 Combination Drugs Banned recently by a gazetteer order Indian Government.

  1. Aceclofenac + Paracetamol + Rabeprazole
  2. Nimesulide + Diclofenac
  3. Nimesulide + Cetirizine +Caffeine
  4. Nimesulide +Tizanidine
  5. Paracetamol + cetrizine + caffeine
  6. Diclofenac + Tramadol + Chlorzoxazone
  7. Dicyclomine +Paracetamol +Domperidone
  8. Nimesulide +Paracetamol dispesible tablets
  9. Paracetamol + Phenylephrine + Caffeine
  10. Diclofenac +Tramadol +Paracetamol
  11. Diclofenac + paracetamol + chlorzoxazone + famotidine
  12. Naproxen+Paracetamol
  13. Nimesulide + serratiopeptidase
  14. Paracetamol +Diclofenac +Famotidine
  15. Nimesulide + Pitofenone + Fenpiverinium + benzyl alcohol
  16. Omeprazole + Paracetamol + Diclofenac
  17. Nimesulide + Paracetamol injection
  18. Tamsulosin + diclofenac
  19. Paracetamol +Phenylephirine +Dextromethorphan +Caffeine
  20. Diclofenac +Zinc Carnosine +Chlorpheniramine
  21. Diclofenac + paracetamol+ chlorpheniramine maleate + magnesium trisillicate
  22. Paracetamol + pseudoephdrine + cetrizine
  23. Phenylbutazone+Sodium Salicylate
  24. Lornoxicam+Paracetamol+Trypsin
  25. Paracetamol +Mefenamic Acid +Ranitidine +Dicyclomine
  26. Nimesulide + Dicyclomine
  27. Heparin +Diclofenac
  28. Glucosamine +Methyl Sulfonyl Methane+Vitamin D3 + Manganese + Boron+ Copper +Zinc
  29. Paracetamol +Tapentadol
  30. Tranexamic Acid + Proanthocyanidin
  31. Benzoxonium Chloride+Lidocaine
  32. Lornoxicam +Paracetamol +Tramadol
  33. Lornoxicam +Paracetamol +Serratiopeptidase
  34. Diclofenac +Paracetamol +Magnesium trisilicate
  35. Paracetamol +Domperidone +Caffeine
  36. Ammonium Chloride +Sodium Citrate +Chlorpheniramine Maleate +Menthol
  37. Paracetamol +Prochlorperazine Maleate
  38. Combikit of 3 tablets of Serratiopeptidase (enteric coated 20000 units) + Diclofenac Potassium & 2 tablets of Doxycycline
  39. Nimesulide +Paracetamol suspension
  40. Aceclofenac +Paracetamol +Famotidine
  41. Aceclofenac + Zinc Carnosine
  42. Paracetamol + disodium Hydrogen Citrate + Caffeine
  43. Paracetamol + DL Methionine
  44. Disodium Hydrogen citrate +Paracetamol
  45. Paracetamol + Caffeine + Codeine Phosphate
  46. Aceclofenac (SR) + Paracetamol
  47. Diclofenac + Paracetamol injection
  48. Azithromycin+Cefixime
  49. Amoxicillin +Dicloxacillin
  50. Amoxicillin 250 mg+Potassium Clavulanate Diluted 62.5 mg
  51. Azithromycin + Levofloxacin
  52. Cefixime +Linezolid
  53. Amoxicillin +Cefixime +Potassium Clavulanic Acid
  54. Ofloxacin +Nitazoxanide
  55. Cefpodoxime Proxetil +Levofloxacin
  56. Combikit of Azithromycin dihydrate, secnidazole and fluconazole
  57. Levofloxacin +Ornidazole +Alpha Tocopherol Acetate
  58. Nimorazole+Ofloxacin
  59. Azithromycin + ofloxacin
  60. amoxycillin + tinidazole
  61. Doxycycline +Serratiopeptidase
  62. Cefixime +levofloxacin
  63. Ofloxacin +Metronidazole +Zinc Acetate
  64. Diphenoxylate +Atropine +Furazolidone
  65. Combikit of Fluconazole Tablet, Azithromycin Tablet and Ornidazole Tablets
  66. Ciprofloxacin +Phenazopyridine
  67. Amoxycillin +Dicloxacillin +Serratiopeptidase
  68. Azithromycin +Cefpodoxime
  69. Lignocaine+Clotrimazole+Ofloxacin+Beclomethasone
  70. Cafuroxime + Linezolid
  71. Ofloxacin +Ornidazole +Zinc bisglycinate
  72. Metronidazole +Norfloxacin
  73. Amoxicillin+Bromhexine
  74. Ciprofloxacin +Fluticasone +Clotrimazole +Neomycin
  75. Metronidazole +Tetracycline
  76. Cephalexin + Neomycin +Prednisolone
  77. Azithromycin + Ambroxol
  78. cilnidipine + metroprolol succinate + metroprolol tartrate
  79. L-Arginine +Sildenafil
  80. atorvastatin + vitamin D3 + folic acid + vitamin B12 + pyridoxine
  81. Metformin+Atorvastatin
  82. Clindamycin+Telmisartan
  83. Olmesartan+Hydrochlorothiazide +Chlorthalidone
  84. L-5-Methylterahydrofolate calcium + Escitalopram
  85. pholcodine +Promethazine
  86. Paracetamol +Promethazine
  87. Betahistine +Ginkgo Biloba Extract+Vinpocetine+Piracetam
  88. Cetirizine Dihydrochloride +Diethyl Carbamazine
  89. Doxylamine +Pyridoxine +Mefenamic Acid+Paracetamol
  90. Drotaverine + Clidinium + Chlordiazepoxide
  91. Imipramine + Diazepam
  92. Flupentixol +Escitalopram
  93. Paracetamol + Prochloperazine
  94. Gabapentin +Mecobalamin +Pyridoxine +Thiamine
  95. Imipramine +Chlordiazepoxide +Trifluoperazine +Trihexyphenidyl
  96. Chlorpromazine +Trihexyphenidyl
  97. Ursodeoxycholic Acid + Silymarine
  98. Metformin 1000/1000/500/500mg +Pioglitazone 7.5/7.5/7.5/7.5mg + Glimepiride 1/2/1/2mg
  99. Gliclazide 80 mg + metformin 325 mg
  100. Voglibose+ Metformin + Chromium Picolinate
  101. Pioglitazone 7.5/7.5mg+Metformin 500/1000mg
  102. Glimepiride 1mg/2mg/3mg+Pioglitazone 15mg/15mg/15mg+Metformin 1000mg/1000mg/1000mg
  103. glimepiride 1mg/2mg+ pioglitazone 15mg/15mg + metformin 850mg/850mg
  104. Metformin 850mg+Pioglitazone 7.5 mg+Glimepiride 2mg
  105. Metformin 850mg+Pioglitazone 7.5 mg+Glimepiride 1mg
  106. Metformin 500mg/500mg+Gliclazide SR 30mg/60mg+Pioglitazone 7.5mg/7.5mg
  107. Voglibose+Pioglitazone+Metformin
  108. Metformin +bromocriptine
  109. Metformin +Glimepiride +Methylcobalamin
  110. Pioglitazone 30 mg+Metformin 500mg
  111. Glimepiride +Pioglitazone +Metformin
  112. Glipizide 2.5mg+Metformin 400mg
  113. Pioglitazone 15mg+Metformin 850 mg
  114. Metformin ER+Gliclazide MR+Voglibose
  115. Chromium Polynicotinate+Metformin Hydrochloride
  116. Metformin Hydrochlopride +Gliclazide +Piogllitazone +Chromium Polynicotinate
  117. Metformin +Gliclazide +Chromium Polynicotinate
  118. Glibenclamide + Metformin (SR)+ Pioglitazone
  119. Metformin (sustainded mg+Glimepride 3mg release)
  120. Metformin (SR) 500mg+Pioglitazone 5mg 500mg+Pioglitazone 15
  121. Chloramphenicol +Beclomethasone +Clomitrimazole +Lignocaine
  122. Clotrimazole + Ofloxaxin + Lignocaine + glycerine and propylene glycol
  123. Chloramphennicol+Lignocain+Betamethasone+Clotrimazole+Ofloxacin+Antipyrine
  124. Ofloxacin +Clotrimazole +Betamethasone +Lignocaine
  125. Gentamicin Sulphate +Clotrimazole +Betamethasone +Lignocaine
  126. Clotrimazole +Beclomethasone +Ofloxacin +Lignocaine
  127. Becloemthasone +Clotrimazole+Chloramphenicol+Gentamycin +Lignocaine Ear drops
  128. Flunarizine + Paracetamole+ Domperidone
  129. Rabeprazole +Zinc carnosine
  130. magaldrate + famotidine + simethicone
  131. cyproheptadine + thiamine
  132. Magaldrate +Ranitidine +Pancreatin +Domperidone
  133. Ranitidine +Magaldrate +simethicone
  134. magaldrate + papain+ fungul diastase + simethicone
  135. Rabeprazole + zinc + domperidone
  136. Famotidine + oxytacaine + Magaldrate
  137. Ranitidine+Domperidone+Semithicone
  138. Alginic Acid+Sodium Bicarbonate+Dried Hydroxide+Magnesium Hydroxide Aluminium
  139. Clidinium +Paracetamol +Dicyclomine +Activated Dimethicone
  140. Furazolidone +Metronidazole +Loperamide
  141. Rabeprazole +Diclofenac +Paracetamol
  142. Ranitidine +Magaldrate
  143. Norfloxacin+ Metronidazole + zinc Acetate
  144. Zinc Carnosine+Oxetacaine
  145. Oxetacaine +Magaldrate +Famotidine
  146. Pantoprazole (as Enteric Coated Tablet)+Zinc Carnosine (as Film Coated Tablets)
  147. Zinc Carnosine+MagnesiumHydroxide +Dried Aluminium Hydroxide+Simethicone
  148. Zinc Carnosine+Sucralfate
  149. Mebeverine Hydrochloride & Inner HPMC capsule (Streptococcus Faecalis +Clostridium butyricum +Bacillus mesentricus+Lactic Acid Bacillus)
  150. Clindamycin +Clotrimazole +Lactic Acid Bacillus
  151. Sildenafil +Estradiol Valerate+Folic Acid
  152. Clomifene Citrate +Ubidecarenone +Zinc+Methylcobalamin +Pyridoxine +Lycopene +Selenium+LevocarnitineTartrate+L-Arginine
  153. Thyroxine + Pyridoxine + Folic Acid
  154. Gentamycin+Dexamethasone+Chloramphenicol+Tobramycin+Ofloxacin
  155. Dextromethorphan + Levocetirizine +Phenylephrine +Zinc
  156. Nimesulide +Loratadine +Phenylephrine +Ambroxol
  157. Bromhexine +Phenylephrine +Chlorepheniramine Maleate
  158. Dextromethorphan + bromhexine +Guaiphenesin
  159. Paracetamol + Loratadine + phenylephrine + Dextromethorphan + caffeine
  160. Nimesulide + Phenylephrine + Ceffeine+ levocetirizine
  161. Azithromycin + acebrophyline
  162. Diphenhydramine +Terpine +Ammonium Chloride +Sodium Chloride+Menthol
  163. Nimesulide+Paracetamol+Cetrizine +Phenylephrine
  164. paracetamol+ loratadine + dextromethophan + pseudoepheridine + caffeine
  165. chlorpheniramine maleate+ dextromethophan+ dextromethophan + guaiphenesin + ammonium chloride + menthol
  166. Chlorpheniramine Maleate+Ammonium Chloride+Sodium Citrate
  167. Cetirizine +Phenylephrine +Paracetamol +Zinc Gluconate
  168. Ambroxol +Guaiphenesin +Ammonium Chloride +Phenylephrine+Chlorpheniramine Maleate +Menthol
  169. dextromethophen + bromhexine + chlorpheniramine maleate + guaiphenesin
  170. levocetirizine + ambroxol + phenylephrine +guaiphenesin
  171. dextromethorphan + chlorpheniramine + chlorpheniramine maleate
  172. cetirizine + ambroxol + Guaiphenesin + ammonium chloride+phenylephrine+ menthol
  173. chlorpheniramine + phenylephrine + caffiene
  174. dextromethorphan + triprolidine + phenylephrine
  175. Terpinhydrate+ dextromethorphan + menthol
  176. dextromethorphan + phenylephrine + zinc gluconate+ menthol
  177. chlorpheniramine + codeine + sodium citarte + menthol syrup
  178. Enrofloxacin + bromhexin
  179. Bromhexine +Dextromethorphan +Phenylephrine +Menthol
  180. Levofloxacin +Bromhexine
  181. Levocetirizine +Ranitidine
  182. Levocetirizine+Phenylephrine+Paracetamol+Ambroxol +Guaiphenesin
  183. cetirizine + dextromethorphan + phenylephrine + zinc gluconate + paracetamol+ menthol
  184. paracetamol+ pseudoephedrine + dextromethorphan + cetirizine
  185. diphenhydamine + guaiphenesin + ammonium chloride + bromhexine
  186. Chlorpheniramine+Dextromethorphan+Paracetamol
  187. Dextromethorphen +Promethazine
  188. Diethylcabamazine +Cetrizine +Guaiphenesin
  189. Pseudoephedrine+Dextromethorphan +Cetirizine+Phenylephrine
  190. Chlorpheniramine +Phenylephrine +Dextromethophan +Menthol
  191. Ambroxol + Terbutaline + Dextromethorphan
  192. Dextromethorphan +Chlorpheniramine +Guaiphenesin
  193. Terbutaline +Bromhexine +Guaiphenesin+Dextromethorphan
  194. Dextromethorphan +Tripolidine +Phenylephirine
  195. Paracetamol +Dextromethorphan +Chlorpheniramine
  196. Pholcodine+Phenylephrine +Promethazine
  197. codeine + levocetirizine + menthol
  198. dextromethorphan + ambroxol + guaifenesin + phenylephrine + chlorpheniramine
  199. Cetirizine +Phenylephrine + Dextromethorphan + Menthol
  200. Roxithromycin + Serratiopeptidase
  201. Paracetamol +Phenylephrine +Triprolidine
  202. Acetaminophen+Loratadine+ambroxol +Phenylephrine
  203. Cetirzine +Acetaminophen+Dextromethorphan +Phenyephrine +Zinc gluconate
  204. Diphenhydramine +Guaifenesin +Bromhexine +Ammonium Chloride+Menthol
  205. Chlopheniramine Maleate +Codeine syrup
  206. Cetirizine +Dextromethorphan +Zinc Gluconate +Menthol
  207. Paracetamol +Phenylephrine+Desloratadine+Zinc Gluconate+Ambroxol
  208. levocetirizine + montelukast + acebrophylline
  209. dextromethorphan + phenylephrine + ammonium chloride + menthol
  210. Dextromethorphan +bromhexine +Guaiphenesin+menthol
  211. Acrivastine+ Paracetamol + Caffeine + Phenylephrine
  212. Naphazoline+carboxy Methyl cellulose +Menthol +Camphor+Phenylephrine
  213. Dextromethorphan +Cetirizine
  214. nimesulide + paracetamol + levocetirizine + phenylephrine + caffeine
  215. Terbutaline +Ambroxol +Guaiphenesin+Zinc+Menthol
  216. Codeine +Chlorpheniramine +Alcohol syrup
  217. Dextromethorphan +Phenylephrine +Guaifenesin+Triprolidine
  218. Ammomium Chloride+Bromhexine +Dextromethorphan
  219. Diethylcarbamazine +Cetirizine +Ambroxol
  220. Ethylmorphine + Noscapine + Chlorpheniramine Maleate
  221. Cetirizine +Dextromethorphan +Ambroxol
  222. Bromhexine +Dextromethorphan +Ammonium Chloride +Menthol
  223. Ambroxol + Guaifenesin + Phenylephrine + Chlorpheniramine
  224. Paracetamol +Phenylephrine +Chlorpheniramine +Zinc Gluconate
  225. Dextromethorphan +Phenylephrine +Cetirizine +Paracetamol +Caffeine
  226. Dextromethophan +Chlorpheniramine +Guaifenesin +Ammonium Chloride
  227. Levocetirizine +Dextromethorphan +Zinc
  228. Paracetamol +Phenylephrine +Levocetirizine +Caffeine
  229. Chlorpheniramine +Ammonium Chloride +Sodium Chloride
  230. Paracetamol +Dextromethorphan +Bromhexine +Phenylephrine+Diphenhydramine
  231. Salbutamol +Bromhexine +Guaiphenesin +Menthol
  232. Chlorpheniramine+Ammonium Chloride +Noscapine +Sodium Citrate
  233. Cetirizine +Dextromethorphan +Bromhexine +Guaifenesin
  234. Diethyl Carbamazine +Chlorpheniramine +Guaifenesin
  235. Ketotifen +Cetirizine
  236. Terbutaline +Bromhexine +Etofylline
  237. Ketotifen +Theophylline
  238. Ambroxol +Salbutamol +Theophylline
  239. Cetirizine +Nimesulide +Phenylephrine
  240. Chlorpheniramine +Phenylephrine+Paracetamol+Zinc Gluconate
  241. Acetaminophen+Guaifenesin+Dextromethorphan +Chlorpheniramine
  242. Cetirizine +Dextromethorphan +Phenylephrine +Tulsi
  243. Cetirizine +Phenylephrine +Paracetamol+Ambroxol +Caffeine
  244. Guaifenesin+Dextromethorphan
  245. Levocetirizine +Paracetamol +Phenylephirine +Caffeine
  246. Caffeine +Paracetamol +Phenylephrine + Chlorpheniramine
  247. Ketotifen +Levocetrizine
  248. Paracetamol +Levocetirizine +Phenylephirine +Zinc Gluconate
  249. Paracetamol +Phenylephrine +Triprolidine +Caffeine
  250. Caffeine +Paracetamol +Phenylephrine +Cetirizine
  251. Dextromethorphan +Phenylephirine +Guaifenesin
  252. Ambroxol + Levocetirizine + Phenylephrine + Guaiphenesin +Menthol
  253. Pseudoephedrine +Cetirizine
  254. Dextromethorphan+Chlorpheniramine+Menthol+Ammonium Chloride
  255. Paracetamol +Caffeine +Phenylephrine +Chlorpheniramine
  256. Salbutamol +Aminophylline +Guaifenesin
  257. Salbutamol +Thoephylline +Bromhexine
  258. Chlorpheniramine+Dextromethorphan+Phenylephrine
  259. Caffeine + Paracetamol+ Chlorpheniramine+Guaifenesin
  260. Ammonium Chloride+Dextromethophan+Cetirizine +Menthol
  261. Dextromethorphan +Paracetamol+Cetirizine +Phenylephrine
  262. Chlorpheniramine+Terpin+Antimony Tartrate+Ammonium chloride+Sodium Citrate+Menthol
  263. Terbutaline Sulphate+Etofylline+Ambroxol
  264. Paracetamol +Codeine +Chlorpheniramine Potassium
  265. Paracetamol +Pseudoephedrine +Cetirizine +Caffeine
  266. Chlorpheniramine +Ammonium Chloride +Menthol
  267. N-Acetyl Cysteine + Ambroxol + Phenylephrine + Levocetirizine
  268. Dextromethorphan +Phenylephrine +Tripolidine +Menthol
  269. Salbutamol +Cetirizine +Ambroxol
  270. Dextromethorphan +Phenylephrine +Bromhexine +Guaifenesin+Chlorpheniramine
  271. Nimesulide +Cetirizine +Phenylephrine
  272. Naphazoline+Chlorpheniramine+Zinc Sulphate +Boric Acid Ip+Sodium chloride +chlorobutol
  273. Paracetamol+Bromhexine +Phenylephrine+Guaifenesin
  274. Salbutamoll+Bromhexine
  275. Dextromethorphan+Phenylephrine+Chlorpheniramine+Guaifenesin +Cetirizine+Acetaminophen
  276. Guaifenesin+ Bromhexine + Chlorpheniramine + Paracetamol
  277. Chlorpheniramine +Ammonium Chloride +Chloroform +Menthol
  278. Salbutamol +Choline Theophylinate +Ambroxol
  279. Chlorpheniramine +Codeine phosphate +Menthol syrup
  280. Pseudoephedrine +Bromhexine
  281. Cetirizine +Phenylephrine +Paracetamol +Caffeine +Nimesulide
  282. Dextromethorphan +Cetirizine +Guaifenesin +Ammonium Chloride
  283. Ambroxol + Salbutamol + Choline Theophyllinate + Menthol
  284. Paracetamol +Chlorpheniramine +Ambroxol+Guaifenesin+Phenylephrine
  285. Chlorpheniramine+Vasaka+Sodium Citrate +Menthol+Tolubalsm +Ammonium Chloride
  286. Bromhexine +Cetrizine +Phenylephrine +Guaifenesin +Menthol
  287. Dextromethorphan+Ambroxol+Chlorpheniramine +Menthol+Ammonium Chloride
  288. Dextromethorphan +Phenylephrine +Cetirizine +Zinc +Menthol
  289. Terbutaline + N-Acetyl L-Cysteine + Guaifenesin
  290. Calcium Gluconate +Levocetirizine
  291. Paracetamol +Levocetirizine+Pseudoephedrine
  292. Salbutamol +Choline Theophylinate +Carbocisteine
  293. Chlorpheniramine +Vitamin C
  294. Calcium Gluconate +Chlorpheniramine +Vitamin C
  295. Chlorpheniramine+Paracetamol +Pseudoephedrine +Caffeine
  296. Guaifenesin +Bromhexine+Chlorpheniramine+Phenylephrine+Paracetamol +Serratiopeptidase (as enteric coated granules)10000 SP Units
  297. Paracetamol +Pheniramine
  298. Betamethasone+Fusidic Acid+Gentamycin+Tolnaftate+Iodochlorhydroxyquinoline(ICHQ)
  299. Clobetasol +Ofloxacin+Miconazole +Zinc Sulphate
  300. Clobetasole +Gentamicin +Miconazole +Zinc Sulphate
  301. levocetirizine + ambroxol + phenylephrine + paracetamol
  302. Permethrin + Cetrimide + Menthol
  303. beclomethasone+iodochlorohydroxyquinone
  304. Neomycin + Doxycycline clotimazole+neomycin
  305. Ciprofloxacin + Fluocinolone + Clotrimazole + Neomycin + Chlorocresol
  306. Clobetasol + Ofloxacin + Ketoconazole + Zinc Sulphate
  307. Betamethasone +Gentamicin+Iodochlorhydroxyquinoline
  308. Clobetasol +Gentamicin+Tolnaftate+Tolnaftate +Idochlorhydroxyquinone+Ketoconazole
  309. Allantoin+Dimethieone+Urea+Propylene+Glycerin+Liquid paraffin
  310. Acriflavine +Thymol+Cetrimide
  311. Betamethasone +Neomycin +Tolnaftate +Iodo Chloro Hydroxy Quinoline +Cholorocresol
  312. clobetasol +Neomycin +Miconazole +Clotrimazole
  313. Ketoconazole+Tea Tree oil+Allantion+zinc Oxide+Aloe Vera+Jojoba oil+Lavander oil+Soap noodles
  314. Clobetasol +Ofloxacin +Ornidazole +Terbinafine
  315. Clobetasol +Neomycin +Miconazole +Zinc Sulphate
  316. Beclomethasone+Neomycin +Tolnaftate +Iodochlorhydroxyquinoline+Chlorocresol
  317. Betamethasone +Gentamycin +Zinc Sulphate +Clotrimazole+Chlorocresol
  318. “Borax +Boric acid +Naphazoline +Menthol +Camphor + methyl hydroxy benzoate
  319. Bromhexine +Dextromethorphan
  320. Dextromethophan +Chlopheniramine +Bromhexine
  321. “Menthol +Anesthetic Ether
  322. Dextrometharphan+Chlopheniramine+Sodium Citrate +Menthol+Ammonium Chloride
  323. Ergotamine Tartrate +Belladona dry extract +Caffeine +Paracetamol
  324. Phenytoin +Phenobarbitone sodium
  325. Gliclazide 40mg+Metformin 400mg
  326. Paracetamol + Ambroxol + Phenylephrine +Chlorpheniramine
  327. Ofloxacin + Ornidazole suspension
  328. Albuterol + Etofylline + Bromhexine + Menthol
  329. Albuterol + Bromhexine + Theophylline
  330. Salbutamol + Hydroxyethyltheophylline (Etofylline)+ Bromhexine
  331. Paracetamol +Phenylephrine +Levocetirizine +Sodium Citrate
  332. Paracetamol +Propyphenazone +Caffeine
  333. Guaifenesin +Diphenhydramine +Bromhexine +Phenylephrine
  334. Dried Alumnium Hydroxide Gel +Propantheline Bromide +Diazepam
  335. Bromhexine +Phenylephrine +Chlorpheniramine +Paracetamol
  336. Beclomethasone +Clotrimazole+Gentamicin+IodoChlorhydroxyquinoline
  337. Telmisartan + Metformin
  338. Ammonium Citrate+Vitamin B 12+Folic Acid+Zinc Sulphate
  339. levothyroxine pyridoxine+ nicotinamide
  340. benfotiamine+ metformin
  341. Thyroid +Thiamine + Riboflavin + Pyridoxine Pantothenate + Tocopheryl Acetate +Nicotinamide + Calcium
  342. Ascorbic Acid + Manadione Sodium Bisulphate+ Rutin + Dibasic Calcium Phosphate + Adrenochrome Mono Semicarbazone
  343. Phenylephrine +Chlorpheniramine +Caffeine +Paracetamol +Bromhexine
  344. Clotrimazole +Beclomethasone +Lignocaine +Ofloxacin +Acetic Acid + Sodium Methyl Paraben +Propyl Paraben

The Controversy Surrounding Paracetamol and Cetirizine

Paracetamol (also known as acetaminophen) is a widely used analgesic and antipyretic. Cetirizine is an antihistamine often prescribed for allergic reactions such as hay fever and urticaria. When used individually, these medications are generally considered safe and effective. However, when combined, they can pose risks due to the potential for overmedication, increased side effects, and reduced therapeutic efficacy.

Reasons for the Ban

  1. Safety Concerns: The primary reason for banning these combination drugs is to address safety concerns. Overuse of Paracetamol, even in combination with other drugs, can lead to severe liver damage. Cetirizine, while effective for allergies, can cause drowsiness and other side effects, which might be exacerbated when combined with other medications.
  2. Ineffectiveness of Combinations: Health authorities have found that certain combinations of Paracetamol and Cetirizine, along with other drugs in the banned list, did not provide additional therapeutic benefits compared to single-ingredient formulations. This makes the combination less justifiable from a medical standpoint.
  3. Regulatory Standards: The Indian government has tightened regulations to ensure that all medications available in the market meet stringent safety and efficacy standards. The banned combinations failed to meet these criteria, leading to their removal from the market.

Implications for Patients

For patients who have been using these combination drugs, the ban necessitates a transition to alternative treatments. It is crucial for patients to consult their healthcare providers to find suitable substitutes that are safe and effective for their specific needs. Medical professionals will guide patients through the process of discontinuing banned medications and transitioning to new treatments.

Implications for Healthcare Providers

Healthcare providers must stay informed about the latest regulatory changes and adapt their prescribing practices accordingly. They should also be prepared to educate their patients about the reasons behind the ban and recommend appropriate alternative medications. Additionally, providers should be vigilant about monitoring patients for any adverse effects or issues arising from the switch in medication.

Implications for the Pharmaceutical Industry

The pharmaceutical industry faces significant changes due to this 156 Combination Drugs Banned. Drug manufacturers and pharmaceutical companies will need to review their product portfolios and reformulate their drugs to comply with new regulations. This might involve extensive research, development, and testing to ensure that new or reformulated products meet the required safety and efficacy standards.

Conclusion

The Indian government’s decision of 156 Combination Drugs Banned, including those containing Paracetamol and Cetirizine, marks a pivotal step toward enhancing public health safety. While this decision may cause temporary disruptions, it ultimately aims to ensure that all medications in the market are both safe and effective. Patients, healthcare providers, and pharmaceutical companies must all play their part in navigating these changes, ensuring that the transition is as smooth and beneficial as possible.

Call to Action

For individuals currently using medications affected by this ban, consult your healthcare provider for guidance on alternative treatments. Stay informed about regulatory changes and continue to prioritize safety and efficacy in your medication choices. If you are a healthcare provider or involved in the pharmaceutical industry, keep abreast of the latest developments to better serve your patients and clients.

References

  1. Indian Government’s Official Announcement on Drug Combinations
  2. Paracetamol: Benefits and Risks
  3. Cetirizine: Uses and Side Effects
  4. Regulatory Standards for Combination Drugs

By staying informed and proactive about such 156 Combination Drugs Banned and more, we can all contribute to a safer and more effective healthcare environment.

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Prashant V @Gymbag4you@gmail.com